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There is nothing to be gained by adding up the number of people who use conventional nicotine replacement therapy (NRT), oral nicotine products like snus, heat-not-burn products like iQOS, vape and combustible cigarettes

But 9 out of 10 of the packs no longer sold in Massachusetts could be tracked to new purchases in neighboring states

Drug Administration Method : Genetic factors can affect how individuals metabolize drugs

Dosimetry, a major issue Different ways to express doses and different dose ranges used When considering the studies dealing with the toxicity of e-cigarettes assessment, in addition to the heterogeneity of e-cigarette products, biological models, or exposure conditions observed, there is also a huge disparity in the doses used as well as in the way they are expressed as shown in Table 2